The Edgbaston club hope to have the left-arm spinner back in time for the start of the new season. The blow rules him out of the inaugural edition of the ILT20 in January.
Danny Briggs will have surgery on a long-term knee issue and miss most of Warwickshire's preparations for the new season.
The 31-year-old was beset by the issue during the regular season, which forced him to have an injection.
Upon returning to pre-season, his cartilage caused more discomfort.
It has been decided that going under the knife to correct is the next option, with the procedure taking place in December.
Briggs, the leading wicket-taker in T20 Blast history, has therefore been ruled out of the inaugural edition of the International League T20 in the United Arab Emirates. He was due to represent Sharjah Warriors alongside Bears teammates Moeen Ali, Chris Woakes and Chris Benjamin.
Briggs is the leading wicket-taker in the T20 Blast (Gareth Copley/Getty Images)
It is hoped he will return in early March ahead of the 2023 season starting the following month.
"It's disappointing for Danny as we know how much he was looking forward to testing his skills in the UAE," said first-team coach Mark Robinson.
"After plenty of discussion with Danny and our physio Mozzy (Gerhard Mostert), we believe this is the best course of action ahead of next season.
"Danny is a valuable member of the squad, who brings leadership on and off the field, so we're looking forward to seeing him return as soon as possible."
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